Episode 10: Isotretinoin, Infertility, and Breakthrough Science | With Dr. Turek & Dr. Amory
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In this powerful episode of Talk With Turek, Dr. Paul Turek and co-host Rob Clyde are joined by Dr. John K. Amory, MD, MPH, Professor of Medicine at the University of Washington, to discuss groundbreaking research that is changing the conversation in male reproductive health.
For men who have been told there is “no chance,” isotretinoin, formerly known as Accutane®, is proving to be a potential game changer. Long used in dermatology, this medication has shown remarkable results in men with little to no sperm production.
Here’s what you’ll learn in this episode:
- A new peer-reviewed study of 30 men with azoospermia or cryptozoospermia showed 37% produced motile sperm after 3–6 months of isotretinoin therapy
- Outcomes went beyond lab results; embryos were created, pregnancies were achieved, and babies were born
- Why retinoic acid is essential to spermatogenesis and how isotretinoin can help restore this pathway
- The importance of careful, specialized oversight given isotretinoin is off-label for male infertility
- How collaboration between experts is breaking stigma and driving innovation in men’s health
